| |
|
 |
Ma XM, Wang Y, Ferraro F, Mains RE, Eipper BA.
Kalirin-7
Is an Essential Component of both Shaft and Spine Excitatory
Synapses in Hippocampal Interneurons. J Neurosci. 2008 Jan 16;28(3):711-24.
De M, Ciccotosto GD, Mains RE, Eipper BA.
Trafficking
of a secretory granule membrane protein is sensitive to copper.
J Biol Chem. 2007;282:23362-71.
Niciu MJ, Ma XM, El Meskini R, Pachter JS, Mains RE, Eipper BA.
Altered
ATP7A expression and other compensatory responses in a murine
model of Menkes disease. Neurobiol Dis. 2007;27:278-91.
Koo TH, Eipper BA, Donaldson JG.
Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating
Rac activation. BMC Cell Biol. 2007;8:29.
Ferraro F, Ma XM, Sobota JA, Eipper BA, Mains RE.
Kalirin/Trio
RhoGEFs Regulate a Novel Step in Secretory Granule Maturation.
Mol Biol Cell. 2007 Dec;18(12):4813-25
El Meskini R, Crabtree KL, Cline LB, Mains RE, Eipper BA, Ronnett GV.
ATP7A
(Menkes protein) functions in axonal targeting and synaptogenesis.
Mol Cell Neurosci. 2007 ;34:409-21.
Sobota JA, Ferraro F, Back N, Eipper BA, Mains RE.
Not
all secretory granules are created equal: Partitioning of soluble
content proteins. Mol Biol Cell. 2006 Dec;17(12):5038-52. Epub
2006 Sep 27. PMID: 17005911
De M, Bell J, Blackburn NJ, Mains RE, Eipper BA.
J Biol Chem. 2006 Jul 28;281(30):20873-82. Epub 2006 May 16.
PMID: 16704972
Schiller MR, Chakrabarti K, King GF, Schiller NI, Eipper BA, Maciejewski MW..
Regulation
of RhoGEF activity by intramolecular and intermolecular SH3
domain interactions. J Biol Chem. 2006 Jul 7;281(27):18774-86.
Epub 2006 Apr 27. PMID: 16644733 [PubMed - indexed for MEDLINE]
Niciu MJ., Ma XM., El Meskini R, Ronnett GV., Mains RE,Eipper BA, .
Developmental
changes in the expression of ATP7A define a critical period
in postnatal neurodevelopment. Neuroscience. 2006;139(3):947-64.
Epub 2006 Mar 23.
Czyzyk TA, Ning Y, Hsu MS, Peng B, Mains RE, Eipper BA, Pintar JE.
Deletion
of peptide amidation enzymatic activity leads to edema and embryonic
lethality in the mouse. Dev Biol. 2005 Nov 15;287(2):301-13.
Epub 2005 Oct 12
El Meskini R, Cline LB, Eipper BA, Ronnett GV.
The
developmentally regulated expression of Menkes protein ATP7A
suggests a role in axon extension and synaptogenesis. Dev Neurosci.
2005;27(5):333-48
Siebert X, Eipper BA, Mains RE, Prigge ST, Blackburn NJ, Amzel LM.
The
catalytic copper of Peptidylglycine alpha-Hydroxylating Monooxygenase
also plays a critical structural role. Biophys J. 2005 Aug 12;
[Epub ahead of print]
Schiller MR, Blangy A, Huang J, Mains RE, Eipper BA.
Induction
of lamellipodia by Kalirin does not require its guanine nucleotide
exchange factor activity.
Exp Cell Res. 2005 Jul 15;307(2):402-17. Epub 2005 Apr 21.
Ferraro F, Eipper BA, Mains RE.
Retrieval
and reuse of pituitary secretory granule proteins. J Biol Chem.
2005 Jul 8;280(27):25424-35. Epub 2005 May 19.
Rabiner CA, Mains RE, Eipper BA.
Kalirin: a dual Rho guanine nucleotide exchange factor that is so much more than the sum of its many parts.
Neuroscientist. 2005 Apr;11(2):148-60. Review.
McPherson CE, Eipper BA, Mains RE
Multiple novel isoforms of Trio are expressed in the developing rat brain.
Gene. 2005 Feb 28;347(1):125-35.
Ma, X, Huang JP, Eipper, BA, Mains RE
Expression
of Trio, a member of the Dbl family of Rho GEFs in the developing
rat brain. 2005 J Comp Neurol 482: 333-348.
Back N, Litonius E, Mains RE, Eipper BA.
Fluoride causes reversible dispersal of Golgi cisternae and
matrix in neuroendocrine cells. Eur J Cell Biol 83: 389-402.
Xin X, Ferraro F, Back N, Eipper BA, Mains RE.
MCdk5 and Trio modulate endocrine cell exocytosis.J Cell Sci.
2004 Sep 15;117:4739-48.
Xin X, Mains RE, Eipper BA.
Monooxygenase X: A member of the Cu-dependent monooxygenase
family localized to the endoplasmic reticulum. 2004 Aug 26 J
Biol Chem 279:48159-48167.
Han M, Park D, Vanderzalm PJ, Mains RE, Eipper BA, Taghert PH.
Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2. J Neurochem. 2004 Jul;90(1):129-41.
Chen P, Bell J, Eipper BA, Solomon EI.
Oxygen activation by the noncoupled binuclear copper site in peptidylglycine alpha-hydroxylating monooxygenase. Spectroscopic definition of the resting sites and the putative CuIIM-OOH intermediate.
Biochemistry.
2004 May 18;43(19):5735-47.
Prigge ST, Eipper BA, Mains RE, Amzel LM.
Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex.Science. 2004 May 7;304(5672):864-7.
McPherson CE, Eipper BA, Mains RE
Kalirin
expression is regulated by multiple promoters. J Mol Neurosci
22: 51-62.
Mair GR, Niciu MJ, Stewart MT, Brennan G, Omar H, Halton DW,
Mains R, Eipper BA, Maule AG, Day TA
A
functionally atypical amidating enzyme from the human parasite
Schistosoma mansoni. FASEB J 18:114-21.
Ma XM, Huang J, Wang Y, Eipper BA, Mains RE
Kalirin,
a multifunctional Rho GEF, is necessary for maintenance of
hippocampal pyramidal neuron dendrites and dendritic spines.
J Neurosci 23: 10593-603.
Chei FY, Eipper BA, Mains RE, Fricker LD
Quantitative
peptidomics of pituitary glands from mice deficient in copper
transport. Cell Mol Biol 49:713-22.
Bell J, El Meskini R, D'Amato D, Mains RE, Eipper BA.
Mechanistic
investigation of peptidylglycine alpha-hydroxylating monooxygenase
via intrinsic tryptophan fluorescence and mutagenesis. Biochemistry.
2003 Jun 17;42(23):7133-42.
Penzes P, Beeser A, Chernoff J, Schiller MR, Eipper BA, Mains
RE, Huganir RL.
Rapid
induction of dendritic spine morphogenesis by trans-synaptic
ephrinB-EphB receptor activation of the Rho-GEF kalirin. Neuron.
2003 Jan 23;37(2):263-74.
El Meskini R, Culotta VC, Mains RE, Eipper BA.
Supplying
copper to the cuproenzyme peptidylglycine alpha-amidating
monooxygenase. J Biol Chem. 2003 Apr 4;278(14):12278-84. Epub
2003 Jan 14.
Steveson TC, Ciccotosto GD, Ma XM, Mueller GP, Mains RE, Eipper
BA.
Menkes
protein contributes to the function of peptidylglycine alpha-amidating
monooxygenase. Endocrinology. 2003 Jan;144(1):188-200.
|
Jaron S, Mains RE, Eipper BA, Blackburn NJ.
The
catalytic role of the copper ligand H172 of peptidylglycine
alpha-hydroxylating monooxygenase (PHM): a spectroscopic study
of the H172A mutant. Biochemistry. 2002 Nov 5;41(44):13274-82.
Kolhekar AS, Bell J, Shiozaki EN, Jin L, Keutmann HT, Hand TA,
Mains RE, Eipper BA.
Essential
features of the catalytic core of peptidyl-alpha-hydroxyglycine
alpha-amidating lyase. Biochemistry. 2002 Oct 15;41(41):12384-94.
May V, Schiller MR, Eipper BA, Mains RE.
Kalirin
Dbl-homology guanine nucleotide exchange factor 1 domain initiates
new axon outgrowths via RhoG-mediated mechanisms. J Neurosci.
2002 Aug 15;22(16):6980-90.
Bruzzaniti A, Mains RE.
Enzymatic
activity of soluble and membrane tethered peptide pro-hormone
convertase 1. Peptides. 2002 May;23(5):863-75.
Ma XM, Mains RE, Eipper BA.
Plasticity
in hippocampal peptidergic systems induced by repeated electroconvulsive
shock. Neuropsychopharmacology. 2002 Jul;27(1):55-71.
Marx R, Mains RE.
Routing
of membrane proteins to large dense core vesicles in PC12 cells.
J Mol Neurosci. 2002 Feb-Apr;18(1-2):113-27.
McPherson CE, Eipper BA, Mains RE.
Genomic
organization and differential expression of Kalirin isoforms.
Gene. 2002 Feb 6;284(1-2):41-51.
|
Gozes I, Brenneman DE, Geppetti P, Kastin AJ, Mains RE, Moody
TW, Seroogy K, Spier AD, Zimmermann M.
Neuropeptides:
brain messengers of many faces. Trends Neurosci. 2001 Dec;24(12):687-90.
Penzes P, Johnson RC, Kambampati V, Mains RE, Eipper BA.
Distinct
roles for the two Rho GDP/GTP exchange factor domains of kalirin
in regulation of neurite growth and neuronal morphology. J Neurosci.
2001 Nov 1;21(21):8426-34.
Hansel DE, Eipper BA, Ronnett GV.
Regulation
of olfactory neurogenesis by amidated neuropeptides. J Neurosci
Res. 2001 Oct 1;66(1):1-7. Review.
Steveson TC, Zhao GC, Keutmann HT, Mains RE, Eipper BA.
Access
of a membrane protein to secretory granules is facilitated by
phosphorylation. J Biol Chem. 2001 Oct 26;276(43):40326-37.
Epub 2001 Aug 27.
Hansel DE, May V, Eipper BA, Ronnett GV.
Pituitary
adenylyl cyclase-activating peptides and alpha-amidation in
olfactory neurogenesis and neuronal survival in vitro. J Neurosci.
2001 Jul 1;21(13):4625-36.
Oyarce AM, Steveson TC, Jin L, Eipper BA.
Dopamine
beta-monooxygenase signal/anchor sequence alters trafficking
of peptidylglycine alpha-hydroxylating monooxygenase. J Biol
Chem. 2001 Aug 31;276(35):33265-72. Epub 2001 Jun 19.
Hansel DE, Quinones ME, Ronnett GV, Eipper BA.
Kalirin,
a GDP/GTP exchange factor of the Dbl family, is localized to
nerve, muscle, and endocrine tissue during embryonic rat development.
J Histochem Cytochem. 2001 Jul;49(7):833-44.
Bell-Parikh LC, Eipper BA, Mains RE.
Response
of an integral granule membrane protein to changes in pH. J
Biol Chem. 2001 Aug 10;276(32):29854-63. Epub 2001 Jun 06.
Hansel DE, Eipper BA, Ronnett GV.
Neuropeptide
Y functions as a neuroproliferative factor. Nature. 2001 Apr
19;410(6831):940-4.
Alam MR, Steveson TC, Johnson RC, Back N, Abraham B, Mains RE,
Eipper BA.
Signaling
mediated by the cytosolic domain of peptidylglycine alpha-amidating
monooxygenase. Mol Biol Cell. 2001 Mar;12(3):629-44.
Penzes P, Johnson RC, Sattler R, Zhang X, Huganir RL,
Kambampati V, Mains RE, Eipper BA..
The
neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing
proteins and regulates dendritic morphogenesis.
Neuron. 2001 Jan;29(1):229-42.
Ma XM, Johnson RC, Mains RE, Eipper BA.
Expression
of kalirin, a neuronal GDP/GTP exchange factor of the trio family,
in the central nervous system of the adult rat.
J Comp Neurol. 2001 Jan 15;429(3):388-402.
El Meskini R, Galano GJ, Marx R, Mains RE, Eipper BA.
Targeting
of membrane proteins to the regulated secretory pathway in anterior
pituitary endocrine cells. J Biol Chem. 2001 Feb 2;276(5):3384-93.
Epub 2000 Nov 01
|
Prigge ST, Mains RE, Eipper BA, Amzel LM.
New
insights into copper monooxygenases and peptide amidation: structure,
mechanism and function. Cell Mol Life Sci. 2000 Aug;57(8-9):1236-59.
Review.
Jiang N, Kolhekar AS, Jacobs PS, Mains RE, Eipper BA, Taghert
PH.
PHM
is required for normal developmental transitions and for biosynthesis
of secretory peptides in Drosophila.
Dev Biol. 2000 Oct 1;226(1):118-36.
El Meskini R, Mains RE, Eipper BA.
Cell
type-specific metabolism of peptidylglycine alpha-amidating
monooxygenase in anterior pituitary. Endocrinology. 2000 Aug;141(8):3020-34.
Driscoll WJ, Konig S, Fales HM, Pannell LK, Eipper BA, Mueller
GP..
Peptidylglycine-alpha-hydroxylating
monooxygenase generates two hydroxylated products from its mechanism-based
suicide substrate, 4-phenyl-3-butenoic acid.Biochemistry. 2000
Jul 11;39(27):8007-16.
Johnson RC, Penzes P, Eipper BA, Mains RE.
Isoforms
of kalirin, a neuronal Dbl family member, generated through
use of different 5'- and 3'-ends along with an internal translational
initiation site. J Biol Chem. 2000 Jun 23;275(25):19324-33.
Penzes P, Johnson RC, Alam MR, Kambampati V, Mains RE, Eipper
BA.
An
isoform of kalirin, a brain-specific GDP/GTP exchange factor,
is enriched in the postsynaptic density fraction.
J Biol Chem. 2000 Mar 3;275(9):6395-403 .
Oyarce AM, Eipper BA.
Cell
type-specific storage of dopamine beta-monooxygenase. J Biol
Chem. 2000 Feb 4;275(5):3270-8.
Ciccotosto GD, Hand TA, Mains RE, Eipper BA.
Breeding
stock-specific variation in peptidylglycine alpha-amidating
monooxygenase messenger ribonucleic acid splicing in rat pituitary.
Endocrinology. 2000 Feb;141(2):476-86.
|
Caldwell BD, Darlington DN, Penzes P, Johnson RC, Eipper BA,
Mains RE.
The
novel kinase peptidylglycine alpha-amidating monooxygenase cytosolic
interactor protein 2 interacts with the cytosolic routing determinants
of the peptide processing enzyme peptidylglycine alpha-amidating
monooxygenase. J Biol Chem. 1999 Dec 3;274(49):34646-56.
Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM.
Substrate-mediated
electron transfer in peptidylglycine alpha-hydroxylating monooxygenase.
Nat Struct Biol. 1999 Oct;6(10):976-83.
Marx R, El Meskini R, Johns DC, Mains RE.
Differences
in the ways sympathetic neurons and endocrine cells process,
store, and secrete exogenous neuropeptides and peptide-processing
enzymes. J Neurosci. 1999 Oct 1;19(19):8300-11.
Bruzzaniti A, Marx R, Mains RE.
Activation
and routing of membrane-tethered prohormone convertases 1 and
2. J Biol Chem. 1999 Aug 27;274(35):24703-13
Mueller GP, Driscoll WJ, Eipper BA.
In
vivo inhibition of peptidylglycine-alpha-hydroxylating monooxygenase
by 4-phenyl-3-butenoic acid. J Pharmacol Exp Ther. 1999 Sep;290(3):1331-6.
Steveson TC, Keutmann HT, Mains RE, Eipper BA.
Phosphorylation
of cytosolic domain Ser(937) affects both biosynthetic and endocytic
trafficking of peptidylglycine alpha-amidating monooxygenase.
J Biol Chem. 1999 Jul 23;274(30):21128-38.
Driscoll WJ, Mueller SA, Eipper BA, Mueller GP.
Differential
regulation of peptide alpha-amidation by dexamethasone and disulfiram.
Mol Pharmacol. 1999 Jun;55(6):1067-76.
Fass DM, Takimoto K, Mains RE, Levitan ES..
Tonic
dopamine inhibition of L-type Ca2+ channel activity reduces
alpha1D Ca2+ channel gene expression. J Neurosci. 1999 May 1;19(9):3345-52.
Spijker S, Smit AB, Eipper BA, Malik A, Mains RE, Geraerts WP.
A
molluscan peptide alpha-amidating enzyme precursor that generates
five distinct enzymes. FASEB J. 1999 Apr;13(6):735-48.
Johns DC, Marx R, Mains RE, O'Rourke B, Marban E.
Inducible
genetic suppression of neuronal excitability. J Neurosci. 1999
Mar 1;19(5):1691-7.
Ciccotosto GD, Schiller MR, Eipper BA, Mains RE..
Induction
of integral membrane PAM expression in AtT-20 cells alters the
storage and trafficking of POMC and PC1. J Cell Biol. 1999 Feb
8;144(3):459-71.
Mains RE, Alam MR, Johnson RC, Darlington DN, Back N, Hand TA,
Eipper BA.
Kalirin,
a multifunctional PAM COOH-terminal domain interactor protein,
affects cytoskeletal organization and ACTH secretion from AtT-20
cells. J Biol Chem. 1999 Jan 29;274(5):2929-37.
Ratovitski EA, Alam MR, Quick RA, McMillan A, Bao C,
Kozlovsky C, Hand TA, Johnson RC, Mains RE, Eipper BA, Lowenstein
CJ.
Kalirin
inhibition of inducible nitric-oxide synthase. J Biol Chem.
1999 Jan 8;274(2):993-9.
|
Kolhekar AS, Quon AS, Berard CA, Mains RE, Eipper BA.
Post-translational
N-glycosylation of a truncated form of a peptide processing
enzyme. J Biol Chem. 1998 Sep 4;273(36):23012-8.
Zhu X, Muller L, Mains RE, Lindberg I.
Structural
elements of PC2 required for interaction with its helper protein
7B2. J Biol Chem. 1998 Jan 9;273(2):1158-64
|
Zhang J, Zheng M, Eipper BA, Pintar JE.
Embryonic
and uterine expression patterns of peptidylglycine alpha-amidating
monooxygenase transcripts suggest a widespread role for amidated
peptides in development. Dev Biol. 1997 Dec 15;192(2):375-91
Darlington DN, Schiller MR, Mains RE, Eipper BA..
The
expression of regulated endocrine-specific protein of 18 kDa
in peptidergic cells of rat peripheral endocrine tissues and
in blood.J Endocrinol. 1997 Nov;155(2):329-41.
Hubbard FC, Goodrow TL, Liu SC, Brilliant MH, Basset P, Mains
RE, Klein-Szanto AJ..
Expression
of PACE4 in chemically induced carcinomas is associated with
spindle cell tumor conversion and increased invasive ability.
Cancer Res. 1997 Dec 1;57(23):5226-31
Marx R, Mains RE.
Adenovirally
encoded prohormone convertase-1 functions in atrial myocyte
large dense core vesicles.
Endocrinology. 1997 Dec;138(12):5108-18.
Schiller MR, Mains RE, Eipper BA.
A
novel neuroendocrine intracellular signaling pathway. Mol Endocrinol.
1997 Nov;11(12):1846-57.
Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM.
Amidation
of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating
monooxygenase. Science. 1997 Nov 14;278(5341):1300-5.
Kolhekar AS, Keutmann HT, Mains RE, Quon AS, Eipper BA.
Phosphorylation
of cytosolic domain Ser(937) affects both biosynthetic and endocytic
trafficking of peptidylglycine alpha-amidating monooxygenase.
J Biol Chem. 1999 Jul 23;274(30):21128-38.
Darlington DN, Schiller MR, Mains RE, Eipper BA.
Expression
of RESP18 in peptidergic and catecholaminergic neurons. J Histochem
Cytochem. 1997 Sep;45(9):1265-77.
Alam MR, Johnson RC, Darlington DN, Hand TA, Mains RE, Eipper
BA..
Kalirin,
a cytosolic protein with spectrin-like and GDP/GTP exchange
factor-like domains that interacts with peptidylglycine alpha-amidating
monooxygenase, an integral membrane peptide-processing enzyme.
J Biol Chem. 1997 May 9;272(19):12667-75.
Milgram SL, Kho ST, Martin GV, Mains RE, Eipper BA.
Localization
of integral membrane peptidylglycine alpha-amidating monooxygenase
in neuroendocrine cells.
J Cell Sci. 1997 Mar;110 ( Pt 6):695-706.
Kolhekar AS, Roberts MS, Jiang N, Johnson RC, Mains
RE, Eipper BA, Taghert PH..
Neuropeptide
amidation in Drosophila: separate genes encode the two enzymes
catalyzing amidation. J Neurosci. 1997 Feb 15;17(4):1363-76.
Mains RE, Berard CA, Denault JB, Zhou A, Johnson RC, Leduc R.
PACE4:
a subtilisin-like endoprotease with unique properties. Biochem
J. 1997 Feb 1;321 ( Pt 3):587-93.
Kolhekar AS, Mains RE, Eipper BA.
Peptidylglycine alpha-amidating monooxygenase:
an ascorbate-requiring enzyme. Methods Enzymol. 1997;279:35-43.
Review. No abstract available.
|
|
Copyright © 2004 by Neuropeptide Lab. All rights
reserved.
|
